Settings changes are applied globally, so any changes apply to the current and future sessions of the CAD toolbox. If for some reason you need to revert to the default bindings, you can delete that stores these settings. The next time the CAD toolbox is opened, the default bindings will be restored. The files are
C:\Users\<name>\AppData\Roaming\CadToolboxPro\<version>\commands.json
C:\Users\<name>\AppData\Roaming\CadToolboxPro\<version>\userPreference.json